Tuesday, July 31, 2012

Panetta: Sanctions not moving Iran away from nukes

TUNIS, Tunisia (AP) ? U.S. Defense Secretary Leon Panetta acknowledged Monday that increasingly stiff international sanctions have yet to compel Iran to give up its nuclear ambitions. But he argued that more pressure eventually would lead Iran to "do what's right."

Iran's disputed nuclear program, which Tehran contends is only for peaceful purposes, is a prominent backdrop to Panetta's five-day tour of the Middle East and North Africa. On Wednesday he'll be in Israel, whose leaders have said they are contemplating a military attack on Iran to stop Iran from developing nuclear weapons, a step they view as a threat to Israel's very existence.

The Obama administration wants Israel to give sanctions and diplomacy more time to steer Iran off its nuclear course, although Panetta repeated the administration's standard line that "all options" are on the table in the event that non-military pressure does not work.

"These sanctions are having a serious impact in terms of the economy in Iran," he told reporters during a visit to the North Africa American Military Cemetery, where 2,841 U.S. servicemen killed in the North Africa campaign against Nazi Germany in 1942-1943 are buried.

"And while the results of that may not be obvious at the moment, the fact is that they have expressed a willingness to negotiate (with the U.S., Britain, France, Germany, Russia and China) and they continue to seem interested in trying to find a diplomatic solution," he said.

Those on-again, off-again negotiations have not come close to resolving a problem that U.S. Republican presidential candidate Mitt Romney has cast as one of the biggest failures of the Obama administration. Romney was in Israel this week showing support for Israel and asserting that if he were president Iran would never get the atomic bomb.

Panetta, who has declined to comment on Romney's visit to Israel, stuck to his argument that the administration's current approach is the right one.

"What we all need to do is to continue the pressure on Iran, economically and diplomatically ... to negotiate and to ultimately do what's right in joining the international family," he added.

After meeting in Tunis with the country's new Islamist leaders, Panetta was headed to Egypt for talks with its new Islamist president, Mohammed Morsi, in Cairo, as well as Egyptian military leader Field Marshal Mohammed Hussein Tantawi.

In his remarks at the U.S. military cemetery, Panetta said Washington plans to promote closer counterterrorism cooperation with Tunisia's new leaders. Panetta's press secretary, George Little, said the Pentagon chief also raised the idea of more U.S. assistance in securing Tunisia's border with Libya and in Tunisian maritime security. Little said specifics were not discussed.

Little said the U.S. is worried about the spread of al-Qaida's influence in North Africa, while adding that "the sense is that the threat here (in Tunisia) is not as great as elsewhere" in the region.

Tunisia was the launching pad for the wave of revolt that swept through the Arab world in 2011. It had one of the most repressive governments in the region. The uprising began in December 2010 when a fruit vendor, Mohammed Bouazizi, set himself on fire in the town of Sidi Bouzid to protest his lack of economic opportunity and the disrespect of the police.

The transition here from dictatorship to democracy has been smoother than in neighboring countries like Libya and Egypt, with no power-hungry military or armed militias to stifle the progress. But there is an increasingly bold ultraconservative Muslim minority who want to turn Tunisia into a strict Islamic state.

Source: http://news.yahoo.com/panetta-sanctions-not-moving-iran-away-nukes-171007337.html

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SSN Kanata Chapter | Ottawa Business Networking | Louis Sanchez ...

Business Networking News and more.

ssnetworking.ca Build stronger business partnerships that will bring you better referrals and increase your brand awareness! SSN Chapters are strategically designed to help Ottawa?s Finest business professionals & entrepreneurs grow their business connections with the RIGHT people to build their business. If your a business professional that does business in and around the Ottawa West/Kanata Area this is the group for you! See current members here: www.ssnetworking.ca SSN strongly believes and emphasizes that ?Your Network is your NETWORTH? meaning that the strength of your business network will give you the best opportunities to receive the highest quality referrals while building a stronger company brand. THIS IS YOUR CHANCE TO SECURE YOUR EXLUSIVE SPOT BEFORE YOUR COMPETITION DOES!!!

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Whitehaven stay-at-home mom builds business on social networking site
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ACLU wants to know how license plate data is used

(AP) ? The American Civil Liberties Union is asking police agencies nationwide for details on how they store data captured by automatic license plate readers, which authorities say help fight crime and terrorism and are not used to stockpile information on all drivers.

A top concern, the ACLU says, is how long the location and movements of people are kept on file after cameras mounted on patrol cars or along roads on telephone poles and bridges photograph license plates. ACLU affiliates in 38 states and the District of Columbia have joined in asking for the information.

"The American people have a right to know whether our police departments are using these tools in a limited and responsible manner, or whether they are keeping records of our movements for months or years for no good reason," said Catherine Crump, staff attorney with the ACLU's Speech, Privacy and Technology Project.

In Maryland, state police keep data from the license plate readers for 24 hours, said Greg Shipley, a police spokesman. Then, the information is forwarded to the Maryland Coordination and Analysis Center, or "fusion center," where local, state and federal authorities work side by side to root out terrorism plots. The data can be kept there for up to a year unless a law enforcement need has been demonstrated in a legal case, said Maryland Assistant U.S. Attorney Harvey Eisenberg, coordinator of the Maryland Anti-Terrorism Advisory Council, which oversees the fusion center.

Officials are trying to strike a legitimate balance in preserving information, and storing the data is no different than preserving evidence in other legal cases, Eisenberg said.

"It's just a much more efficient and effective way to do that," Eisenberg said.

The ACLU said that while the use of the technology is growing around the nation, too little is known about how long the data can be stored.

"The concern is about 'Big Brother' and police potentially maintaining large databases about where innocent citizens drive every day," said Dane Claussen, executive director the ACLU office in Las Vegas.

The ACLU of Nevada is filing requests seeking records from some of the state's largest law enforcement agencies, including Las Vegas Metropolitan, Reno and Henderson city police and the Washoe County sheriff, Claussen said.

In Henderson, outside Las Vegas, city police reported success shortly after installing mobile license plate scanners in several marked patrol vehicles in June 2011. The first case involved an officer driving on a busy boulevard identifying a Chevrolet pickup as having been reported stolen in Las Vegas.

Henderson police spokesman Keith Paul said Monday his agency had not yet been asked by the ACLU for information.

In New Mexico, license plate readers are installed at the five points of entry where commercial truckers stop when they pass through the state. The readers check the truck's license plate and tap into government crime, safety and tax databases.

State inspectors are provided with information on whether the license plate is wanted in connection with a crime, according to New Mexico State Police Chief Robert Shilling. Inspectors also get real-time reports on the safety records of the trucking company and the individual truck, and whether state road taxes have been paid.?The information is retained by the Department of Public Safety for six months and then deleted, Shilling said.

"We don't use it except for criminal justice purposes," said Shilling.

Vernon Herron, a retired commander of the Maryland State Police, said law enforcement's focus is on solving crimes, not storing piles of data for the sake of compiling information. The cameras have been instrumental in significant reductions in auto thefts and locating missing children through Amber Alerts, said Herron, who is now a policy analyst for the Center for Health and Homeland Security at the University of Maryland, Baltimore.

"It has been very successful in returning kids to their families," said Herron, who worked for 27 years with the Maryland State Police and as public safety director for Prince George's County. In that county, auto thefts were cut by about 40 percent in two years with the help of the cameras.

___

Associated Press writers Ken Ritter, in Las Vegas, and Barry Massey, in Santa Fe, N.M., contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-07-30-Vehicle%20Tags-ACLU/id-db9f7505d3a44d7ab15cf82a31f49cfb

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Do You Care For Your Neck, Chest, Hands, Lips, And Teeth ...

Women have a bagful of anti aging skin care products for the face. The bag generally contains facial cream, night cream, under-eye cream, exfoliants, deep wrinkle cream, cleansers, toners, and many more.

What about the area below your jaw bone, such as your neck, chest, and hands? You also got creams for the cheeks, forehead, nose, under eye area, and chin. What about your lips and teeth?

Aren?t they affected by aging? Do you have a solution to keep them young and healthy?

Neck and chest

You might have seen photographs of ladies with glowing faces, though when you gaze downwards, their neck reveals their age. The sagging, dull skin screams of neglect. The chest is prone to sun damage too. When you wear those plunging necklines, your chest gets exposed to direct sun. You apply sunscreen and moisturizers only on the face and forget about your neck.

Constant exposure leads to hyper pigmentation or sun spots. The skin at the chest becomes thinner and loses its sheen. It is high time you began applying moisturizers with SPF on your neck and chest. In case aging has already started showing, use good anti wrinkle products for this area.

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Source: http://www.akcesoria-kosmetyczne.pl/skin-care/do-you-care-for-your-neck-chest-hands-lips-and-teeth/

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$1250000 :: 18025 Skyland CIR, Lake Oswego OR, 97034 ? Lake ...

Property Photo

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4 beds, 4 full, 2 part baths
Home size: 5,379 sq ft
Lot Size: 40,075 sq ft
Property Type: DETACHD
MLS Number: 12302634
Community: Skylands

Excellent pricing, fabulous location and gorgeous views combine to make this an amazing opportunity in sought after Skyland?s neighborhood. Wonderful updates and reconfigured lower level include strand bamboo floors, new bathrooms, Anderson windows and more. Views and in-ground pool round off this complete package.

Listed with Hasson Company Realtors


Brought to you by Chris Larsson, Coldwell Banker Seal. Call me today at 503-683-2897!

The content relating to real estate for sale on this web site comes in part from the IDX program of the RMLS? of Portland, Oregon. All real estate listings are marked with the RMLS? logo, and detailed information about these properties includes the names of the listing brokers. Listing content is ? 2009 RMLS?, Portland, Oregon.


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Chris Larsson- Lake Oswego Real Estate Agent

Let me help you find everything you need to know about buying or selling real estate in Lake Oswego, OR! I have been a top-producing Coldwell Banker real estate professional for over 8 years in LO. I am 120% dedicated to providing world-class concierge level service to my clientele.


SEARCH THE LAKE OSWEGO MLS AND REAL ESTATE LISTING HERE...

Source: http://www.97034realestate.com/blog/1250000-18025-skyland-cir-lake-oswego-or-97034-lake-oswego-homes-for-sale-lake-oswego-real-estate-97034-lake-oswego-real-estate-agent/

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WOKVNews: It's a busy ride on 95 NB between University and Atlantic Blvd. There's a crash at Atlantic on the shoulder. #wokvtraffic

Sorry, Readability was unable to parse this page for content.

Source: http://twitter.com/WOKVNews/statuses/229918691767230466

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Give a thought to Windows Leeds











If you are thinking of altering your windows and doors then in the article below you will certainly find an option worth looking into. It's not mere windows and doors but you can now get different colored Windows Leeds, UPVC windows, Double Glazing Leeds etc.

Leeds is not the only thing that is available throughout West Yorkshire and Yorkshire in Bradford, Huddersfield Halifax. They are also across the UK. For finding the one you can go to glasstecwindows.co.uk, but before that let's read more about it.

The best thing about these windows is that it adds value to your possessions and makes it more valuable than ever before. It shields your home even when you will not present. Several options like single doors that open can both in and out, doors with fanlight, energy saving doors and sidelight frames etc. So you can lessen the cost of electricity bill also. In short we can say that Windows Leeds is cost efficient also.

It gives pretty astonishing and elegant look to your home and also doesn't require much maintenance and care. It is a fact that mostly purchasers want to purchase that property that is equipped with UPVC windows. If we see composite or Double Glazing Leeds from maintenance point of view then also it is better than timber doors.

The finishing and clarity that you get in Windows Leeds, you can't get that in timber doors. They don't keep same designs of product but offer only single piece of one design. After clearing all your confusions regarding Trade windows, if you really impressed with its numerous features then Don't waste your time and get it installed in your home as soon as possible to ensure safety of you and your property.

It is very well known for its energy saving and thermal insulation feature in both the seasons. So you don't have to us AC in summer. They have a special thing that is trade counter where you will find competitive prices with their several new offers.

Glass tec windows situated in Bradford, west Yorkshire is the name of a leading and ever growing manufacture in the field of home improvement accessories such as door and windows. Here you can get stock not only for your resident but also for your commercial place like office, company.

Glass Tec Windows 82 Richmomd Road Bradford, West Yorkshire BD7 1DL Contact us: - 01274 742280

Html about author:- Go to glasstecwindows.co.uk for highest quality of Doors Bradford and Windows Bradford. As they provide their services in wide range of areas.

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Cancer Drugs: Value for the Money?. In the Pipeline:

And while we're talking oncology, here's a piece from Luke Timmerman at Xconomy that brings up a lot of tough questions. We've talked about some of these before around here, but everyone who works in oncology drug discovery is going to hear them again: How much should a new cancer therapy cost? Who's going to pay for it? Are patients (and their insurance companies) getting value for their money?

I wouldn?t go so far as to say we need a draconian system to discourage drug developers from creating new products. Drug prices are rising fast, but there are a lot of other factors contributing to increased healthcare spending. Drug companies can, and should, be able to recoup the investments they make in the form of high drug prices. But if you?re going to charge a high price for a drug, I think a company needs to have a much stronger value proposition than ?Hey, we shrank tumors in half for 20 percent of patients. Now hand over your $100,000.? It needs to be more like, ?Hey, my drug has an 80 percent chance of helping people with this genetic profile, and those people can expect to live an extra year, with high quality of life.? Now you?re starting to really talk about $100,000 of value.

Sadly, drug companies tend to be more interested in satisfying the short-term profit desires of their investors than they are in truly delivering cost-effective care to patients. . .

Well, it's like this: we realize that people want inexpensive drugs that work great. But we have an awful time delivering anything like that. As I've said before here, we keep swinging for those fences and missing. That's why these drugs come out, the ones that only extend life span for a limited amount of time: every one of those are drugs that people had higher hopes for, but that's how they performed in the real world, so out they come onto the market to do as best they can. And if they're only going into a small patient population, then the pricing gets set accordingly.

So we have two trend lines that are trying to intersect: the amount of money one can hope to recoup from a new cancer medication, and the amount of money that it takes to find one. They haven't quite crossed, not yet, but they're on course to. If it were less costly to develop these things, or if they delivered more value in the end, we could push them back apart. Will either of those be realized in time to help?

Source: http://pipeline.corante.com/archives/2012/07/30/cancer_drugs_value_for_the_money.php

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Come On People! Celebrities Have Feelings Too! (VIDEO)

Come On People! Celebrities Have Feelings Too! (VIDEO)

There are quite a few cool things about being a celebrity. They receive tons of free stuff even though they are making gobs of money. [...]

Come On People! Celebrities Have Feelings Too! (VIDEO) Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2012/07/come-on-people-celebrities-have-feelings-too-video/

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Icom UK, 'Official Radio Communications Supplier' - British Marine ...

Icom UK, ?Official Radio Communications Supplier? to Ramsgate Week 2012

29 July 2012

Icom are pleased to be continuing their support of Ramsgate Week which will be held between 30th July ? 4th August 2012 this year. Icom are once again proud to be named as the ?Official Radio Communications Suppliers? to the regatta which has been a feature of the town?s calendar for over 110 years. Ramsgate Week 2012 is widely recognised as the friendly regatta and the alternative to Cowes and attracts approximately 100 boats from Great Britain and the continent.

Icom UK will be supplying the regatta with Icom marine handheld VHF radios, which will be used by the safety fleet and on shore organisers in the management of Ramsgate Week. The radios will be the primary means of communication for the race management team, race control and safety fleet. The Icom handhelds will be used by officials to oversee events both on and off the water, and will also be used to respond quickly and efficiently to any emergencies that may arise.

Organised by the Royal Temple Yacht Club, Ramsgate Week is the third largest international regatta in the UK, featuring about 100 boats from Great Britain and overseas. For more details of this year?s event, please go to www.ramsgateweek.com.

Source: http://www.bmea.org/news/2012/icom-uk-official-radio-communications-supplier-to-ramsgate-week-2012/

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Car Dealers: Are You Using Dealership Courtesy Shuttle Van Wraps ...

Chevy Express Courtesy Shuttle VanSome of our customers at Sunrise Signs are indeed franchised auto dealerships and most dealerships own a courtesy shuttle van to take customers to work or home while their vehicles are being repaired and to pick them up when the job is complete. So, what is the best way to get your shuttle van noticed? Van wraps!

Auto dealerships spend a lot of advertising dollars on TV and radio spots and those two-page full color ads in local newspapers. While these ads may be necessary, they do eat up a large part of any advertising budget.

Here?s a quick fact for you dealership owners and managers: According to 3M, ?A company would need to spend $130,000 in advertising dollars to produce the same effects of a $3,500 vehicle wrap? and that includes dealership courtesy shuttle van wraps!

Visual Solutions

Vehicle graphics and wraps do get noticed. The American Trucking Association (ATA) says, ?91 percent of people surveyed do notice vehicle graphics.? If you?re in charge of the courtesy shuttle van at your dealership, think about your commute to and from work. Do you see graphics on trucks, cars, SUVs and vans all displaying visual information on what a company does?

Ford Transit Connect with Shuttle Van WrapsWe bet you see landscapers, exterminators and contractors all with graphics revealing what they do with friendly catchphrases like ?family owned and operated? or ?free estimates? or ?we serve the entire Tri-State area.? Along with these graphics, you?ll also see website URLs, QR (quick response) codes, and even Twitter handles such as @sunrisewraps and other information like ?Find us on Facebook.? Other graphics may include a menu of products and services offered right on the wrap.

At Sunrise Signs we think the best part of any dealership courtesy shuttle van wraps are the graphics embedded onto the wraps. The graphics convey what you do visually and leave a lasting impression on the eyes (and minds) that view them.

In fact, here?s another statistic: The Traffic Audit Bureau for Media Measurement says ?A (graphic wrapped vehicle) can generate between 30,000 to 70,000 impressions daily. Ask yourself this question. Are you getting that many ?impressions? and potential customers from TV/Radio or newspaper ads? Probably not. Here is where Sunrise Signs can help your auto dealership?no matter what manufacturer of vehicles you sell?even if you sell more than one!

Templates, Logos, Design and More!

Place a Mustang on your courtesy shuttle van wrapsWe?ve done dealership courtesy shuttle van wraps before and our in-house graphic designers are able to design and create your graphics and van wraps by using the many manufacturer templates we have for a wide variety of models.

Of course we work closely with your dealership representative to ensure the graphics are exactly what you want and as far as installation goes?no need to worry if your store isn?t located near us. We have partnered with over 250 certified shuttle van wrap installers so while we design, create and print your van wraps we can also ship them almost anywhere in the United States and ask one of our certified installers to ensure the wraps are placed without flaws, broken seams or bubbles. We take pride in our expertise!

Say you?re a Ford dealer?wouldn?t a 2013 Mustang Boss 302 look awesome across the side of your van wraps? What if you?re a Dodge dealership? Wouldn?t a Dodge Charger SRT8 or Dodge Challenger look incredible on your van wraps?

And, because van wraps last up to five years and are 100 percent removable, when it?s time to put that shuttle van on your lot for sale to the public, the wraps are easily removed?and they protect the original manufacturer paint!

Franchise Branding

Courtesy Shuttle Van WrapsIf your courtesy shuttle van is void of any vehicle graphics or wraps or perhaps it?s only got a magnetic sign with print so small visual impressions are almost impossible, we invite you to contact us to let us show you how we can turn your customer shuttle van into a 24/7 moving billboard advertisement.

Your franchisor gives you unlimited access to the artwork you need and that?s all we need! In fact, we invite you right now to take a look at some of our Success Stories to see how outstanding some of our wraps really are and our customers are always satisfied with our quality work.

If you still need some convincing, download our Vehicle Wrap ROI Calculator to see how fast the dollars invested will get you what you want?more customers.

We also have a helpful and free Vehicle Wrap Information Kit to help you understand how van wraps are designed, printed and installed.

We Don?t Like to Brag But?

Car dealership courtesy shuttle van wrapsWithout customers consistently visiting your store, your job as a dealership owner or manager is to find unique (and affordable) ways to get them to the dealership. If you?re smart your already blogging and using social media like Facebook and Twitter to increase your online visibility and build your brand identity, but you also need to consider the visuals you can gain on the streets: 30,000 to 70,000 impressions daily!

Part of every full service sign and vehicle graphics and wrap enterprise is to help customers build their brand, market the brand and turn the investment made into vehicle wraps into real-life customer revenues.

Ready for a quote? Ready to get your dealership courtesy shuttle van wrapped? We thought so!

get-a-free-courtesy-shuttle-van-wrap-quo

Image Credits:

2013 Ford Mustang Boss 302 and Ford Transit Connect/courtesy Ford Media Room/J.Scheid/registered user.

2013 Chevy Express via GM Media Center/J.Scheid/registered user.

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Source: http://1minutegetaway.com/estremozmarca/2012/07/30/car-dealers-are-you-using-dealership-courtesy-shuttle-van-wraps/

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Penn State likely will loan money to pay NCAA fine

WASHINGTON (AP) ? The president of Penn State says the university will probably have to give its athletic department a long-term loan to pay the $60 million fine imposed by the National Collegiate Athletic Association in light of the child sex abuse scandal.

Rodney Erickson told CBS's "Face the Nation" program in a broadcast aired Sunday that a combination of funds including the football program's financial reserves will be used to pay the fine.

Asked whether Penn State had put too much emphasis on football, Erickson called the athletics program "a tremendous success" but said some parts perhaps "became too much areas unto themselves."

Erickson also said people will have to judge for themselves the legacy of longtime coach Joe Paterno, but he said he believes the coach's educational legacy will stand.

Source: http://www.msnbc.msn.com/id/48383942/ns/local_news-delaware_valley_pa_nj/

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No settlement deal for HCDE election screwup (Offthekuff)

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Monday, July 30, 2012

Reduced Impact Cardiovascular For The Optimum Health and fitness

In today?s community there is a lot of stress placed on excess weight and exercise. Sometimes fitness may seem like a hopeless target to achieve. Though it demands responsibility and function, it is actually faraway from impossible! With one of these easy tips, you?ll be moving toward a fit and healthy you.

One particular (and cost-cost-free) type of exercising you can do is pushups. Pushups are relatively easy to do. You simply spot both of your hands on the floor, spread shoulder joint thickness separate, both feet on a lawn, and drive the body up and downwards. Pushups are an excellent workout for your chest and arms.

When working out, a great idea is to be positive you warm-up your mind. The reason for it is because your central nervous system lets the muscles know when you ought to contract. One method for you to do this is simply by standing upright on one lower leg when squatting, and after that effect the floor together with your opposite hand.

Getting in form is not merely about exercising. To have the best from your instruction schedule, you should also change how you live. Which means you must stop smoking, make better healthy selections and stay a lot more lively on a daily basis. A good way of living can make exercising much simpler.

When you have made a decision that you would like to begin working there is not really significantly you need. As opposed to other sports and routines you simply will not require a lot of items. Because of all the money you are saving you have to be positive to get an excellent couple of running footwear.

Work with retaining your muscles limber by retaining your stretches. For all those below 40, consider retaining your expands for approximately 30 seconds. For all those over 40, attempt retaining them for approximately 60 seconds. The explanation for time big difference is muscle tissues get rid of their pliability while you get older and might grow to be strained or receive trauma more easily than when you?re more youthful.

You require tight footwear to go up rocks. If you plan to provide rock and roll or wall structure ascending in your fitness program, tend not to pick your shoes or boots the way you would choose working or wandering shoes or boots. Climbing shoes should be so tight that you could not go walking pleasantly inside them. Handle and awareness are paramount in climbing shoes.

As the starting of this information has reviewed, stepping into far better condition is a type of goal that numerous folks reveal. Even so, a lot of people by no means improve their private physical fitness because they are not provided with the correct advice or information and facts. Utilize this article?s assistance and be soon on your way increasing your private health and fitness.

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Source: http://www.articledumpster.com/reduced-impact-cardiovascular-for-the-optimum-health-and-fitness/?utm_source=rss&utm_medium=rss&utm_campaign=reduced-impact-cardiovascular-for-the-optimum-health-and-fitness

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No settlement deal for HCDE election screwup (Offthekuff)

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Fruit flies light the way for scientists to pinpoint genetic changes that spell cancer

Fruit flies light the way for scientists to pinpoint genetic changes that spell cancer

Monday, July 30, 2012

By studying fruit flies, scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have successfully devised a fast and cost-saving way to uncover genetic changes that have a higher potential to cause cancer. With this new approach, researchers will now be able to rapidly distinguish the range of genetic changes that are causally linked to cancer (i.e. "driver" mutations) versus those with limited impact on cancer progression. This research paves the way for doctors to design more targeted treatment against the different cancer types, based on the specific cancer-linked mutations present in the patient. This study published in the prestigious journal Genes & Development could help advance the development of personalised medicine in cancer care and treatment.

The era of genomic sequencing has generated an unparalleled wealth of information on the complexity of genetic changes that occur as cancer develops and progresses. "Many genetic changes arise in cancer cells and changes continue to accumulate during the progression of disease to metastatic cancer [1]. The current challenge is to understand which of the many genetic changes are important drivers of disease progression" said Dr. Stephen Cohen, Principal Investigator at IMCB and team leader of this paper.

Though very different in many ways, fruit flies and humans share similarities in a remarkable two-thirds of their genomes. That is to say, many of the genes found in humans are also present in the flies. Similarly, various signalling pathways involved in tumour formation are also well conserved from fruit flies to humans. In fact, previous studies have shown that about 75 percent of known human disease genes have a recognisable match in the genome of fruit flies [2].

Leveraging on their genetic similarities, Dr H?ctor Herranz, a post-doctorate from the Dr Cohen's team developed an innovative strategy to genetically screen the whole fly genome for "cooperating" cancer genes. On their own, these are the genes that appear to be harmless and have little or no impact on cancer. But in fact, they cooperate with other cancer genes, so that the combination causes aggressive cancer, which neither would cause alone.

In this study, the team was specifically looking for genes that could cooperate with EGFR [3] "driver" mutation, a genetic change commonly associated with breast and lung cancers in humans. SOCS5, reported in this paper, is one of the several new "cooperating" cancer genes to be identified through this innovative approach. Most of these new-found genes have yet to be identified as cancer genes in human or mouse models.

Said Mr Xin Hong, a PhD student and the co-first author of this paper, "We were very surprised by our finding because this it the first time that the Socs gene family is found to be linked to cancer. Previously it has only been associated with immunological disorders."

Dr. Cohen added, "Though these studies are in the early stages, they are very promising. Already, there are indications that levels of SOCS5 expression are reduced in breast cancer, and patients with low levels of SOCS5 have poor prognosis."

The IMCB team is preparing to explore the use of SOCS5 as a biomarker in diagnosis for cancer.

Said Professor Wanjin Hong, Executive Director of IMCB, "This study sheds light on the complexities of cancer genetics and paves the way to accelerate development of personalised medicine in cancer care. It is a fine examples of how powerful genetic approach using the fly model can reveal molecular mechanisms underlying human cancer. More importantly, it shows how fundamental research can have far-reaching applications for potential clinical benefits."

###

[1] Cancer metastasis is the rapid and often fatal spread of cancer cells from the primary tumour to other parts of the body, and is often the leading cause of death by cancer.

[2] Reiter, LT; Potocki, L; Chien, S; Gribskov, M; Bier, E (2001). "A Systematic Analysis of Human Disease-Associated Gene Sequences In Drosophila melanogaster" Genome Research 11(6):1114-1125 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC311089/?tool=pmcentrez

[3]Epidermal growth factor receptor (EGFR) is a cell surface protein that binds epidermal growth factor binds, causing cells to divide. It is found at abnormally high levels on the surface of many types of cancer cells, so that these cancer cells may divide excessively in the presence of epidermal growth factor

Agency for Science, Technology and Research (A*STAR), Singapore: http://www.a-star.edu.sg

Thanks to Agency for Science, Technology and Research (A*STAR), Singapore for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/122136/Fruit_flies_light_the_way_for_scientists_to_pinpoint_genetic_changes_that_spell_cancer_

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Improve Your ghds Self Improvement With This Assistance ...

Personal development varies from alterations you intend to make within your specialist daily life to modifications you intend to make at home cheap ghd straghteners daily life. Regardless of which part of you life you want to center on, shifting 1 practically generally overlaps in the other. This article provides you with some actionable tips that can be used with your self improvement quest.

Recognize your flaws and take them. People have flaws. It is essential to acknowledge the problems that are your own personal. Acknowledge your largest, most obtrusive defects. You should even make time to recognize the tiny versions. Work to solution any flaws that can be fixed and just agree to the ones that are unable to.

Continue to keep learning self improvement resources to recognize new tips, sustain concentrate and get inspiration. You will find loads of textbooks, tapes and videos on the market to be of assistance in hitting your targets. Simply by making a habit of looking at these sources it is possible to grab new tips and tricks to create ghds your own personal development program more productive.

Be correct for your personal, and be the best ?you? probable. Tell the truth about what you should be satisfied and delighted, and refuse those activities which do not take real pleasure into your life. Be the best ?you? that snacks oneself with admiration, enjoy and compassionate. In the event that variation of yourself is not going to but really exist, focus on locating and building it.

In relation to self improvement make certain you stand for what you consider in but that you do not inflict hurt on on your own or other folks at the same time. It is essential to not way too superior or highly effective simply because you cannot lead if others are fearful of you.

Religious beliefs may help some individuals. Possibly the religion you had been brought up ghds in will not be for you personally should you take into account oneself an atheist. Certain people see faith as a means of finding their area in the world, plus some men and women look at it in an effort to increase their daily living by taking on a particular approach.

An excellent self improvement tip would be to understand and admit to on your own that there exists a huge space in between exactly where your daily life is now and that you want it to be. Should you not accept and acknowledge your current scenario, you will get absolutely no way of changing and improving your lifestyle.

Talk about your knowledge with other individuals. Don?t hold back information and facts that ghds other people are able to use to better their day-to-day lives. Be selfless with information and facts and let all those near you to succeed correct along with you. When you present other people you are happy to reveal whatever you know, they will reciprocate by expressing the things they know with you, and everybody will manage to benefit.

As mentioned at the outset of this informative article, personal development runs the gamut of behaviours and activities you need to alter. If you are working on your conversation capabilities both at home and operate or centering on cheap ghd straghteners time management to provide a greater job life balance, use the information provided in this post to create the search for advancement less difficult.

10 years on from revolutionising ghds with the introduce of their initial straightener, http://www.ghdstraightenerssale-uk.org is always in keeping with its starting ethos: the actual character of modification.

Source: http://answers.apostoliccm.com/2012/07/improve-your-ghds-self-improvement-with-this-assistance/

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Fantastic Vacations With Tucan Travel

For almost 25 years, Tucan travel as been providing incredible adventure trips to breathtaking destinations around the world. They are an award winning company that prides themselves on excellent service and keeping customers satisfied. There are numerous options available so there is always something that is guaranteed to be the perfect choice.

Vacation packages of all sorts are available for individuals as well as groups. They also provide stimulating Expedition Cruises for those seeking adventure. There are over 470 different choices of all types and to various amazing destinations from which to pick. Locations include Europe, Asia, Russia, Latin America, the Middle East and multiple locations on the African continent. They even offer a most exotic excursion to the mystical land of Antarctica.

This company specializes in providing clients with exciting vacation packages of excellent quality at a price that is easy on the wallet. They are experts at working on a budget to allow others to experience these amazing locations. To make things even more enticing, there are several ways to earn discounts on tours such as booking the journey at least 6 months early or setting up multiple gigs during the same session. Groups with more than 3 members and repeat customers can also receive special price cuts.

Clients can feel safe booking with Tucan travel because they are so confident in their services. The company has been owned by the same British-Australian partnership that has independently operated it since 1987. This just goes to show that the agency is stable and reliable. While others may come and go, this one is here to stay. They even have a social presence on top sites like Facebook and Twitter.

Anyone who books through the company should feel safer knowing that their investment is financially backed by AITO Trust as well as ATOL and TCF Australia. The staff can guarantee the quality of the service received on the trip since the agency personally handles more than 95% of their group tours with very little relying on outside assistance. Handling everything themselves allows Tucan to be sure all issues are rectified in a timely and satisfying manner.

There is no shortage of talent on the staff at this company. Every member has a vast store of travel expertise from which to draw and ensure that they are doing what is necessary to keep clients happy, satisfied and enjoying the most amazing experience possible. They are friendly and knowledgeable when introducing the breathtaking landscapes, interesting cultures and people at every location.

Being socially responsible as well as environmentally efficient, the company takes pride in giving quality experiences. They are held to very high standards of excellence and are carefully trained in customer relations. Guests will never have to complain about the ratty rental they had to ride in because the agency owns, operates and maintains its own complete fleet of luxury expedition vehicles.

An extensive supply of reserved departure dates means that Tucan travel can easily accommodate most any size tour group. It does not matter if a lone traveler is looking for a jungle adventure or if a circle of friends is wishing to spend some time getting away from it all, everyone will be given personalized attention. There are very few places a person can get this level of excellence at an affordable rate.

About the Author:
You can find details about the benefits you get when you book Antarctica tours and more information about the Tucan Travel team at http://www.tucantravel.com/destinations/latin-america-and-antarctica now.

Source: http://www.articlesnatch.com/Article/Fantastic-Vacations-With-Tucan-Travel/4068923

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Family Home and Life: Grandparents Say It Saturday - Leifbrady's blog

Hello all! Can you believe school has started for some kids already? My Oldest grand daughter is starting school next Wednesday and that?realization hit me hard! I had looked forward to summer so I could spend more time with her and already it's over! I'm sorry to say I didn't do half the things with her I had planned. I have a few days left so hopefully I can?check off?a few more items on my list. Where does the time go?

Thanks so much for coming by; we have had a few new linkers and I hope you enjoyed getting to know a little about them. It is fun to find a grandparent blogger we had not known about before isn't it? I think there must be lot of us?out there! So with that, here we go! Can't wait to see what you link up this time!

Be sure to add yourself to the Grandparent Blogger Directory if you haven't yet. Remember, if you are of grand parenting age and blog, you are eligible here even if it is not about grand parenting; please just keep it family friendly :)

Add your link here every Saturday at Grandparent's Say It Saturday.

  • Please only link to a post, not to your home page.
  • Please link that post back to Family Home and Life
  • Link up to 3 post
  • While you are here check out other linkers and leave some comments
  • Consider following fellow linkers as well as me
  • No Esty Shops or give aways
  • This link is closing on Monday night.
  • I have a new Grandparent Blogger Directory, I hope you will add your blog there
Be sure to visit Lisa at Grandma's Briefs to join her linky, GRAND Social, on Mondays. Thanks for linking up with me!

Copyright? Family Home and Life 2012 All Rights Reserved

Source: http://www.familyhomeandlife.com/2012/07/grandparents-say-it-saturday_28.html

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Source: http://leifbrady.typepad.com/blog/2012/07/family-home-and-life-grandparents-say-it-saturday.html

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S.Africa rate cuts can't be taken for granted:Marcus

DURBAN (Reuters) - Further interest rate cuts in South Africa will depend on growth and inflation in coming months and should not be taken as a given, central bank Governor Gill Marcus reiterated on Saturday.

The Reserve Bank unexpectedly reduced rates by 50 basis points to 5.0 percent last week, citing concerns about the effect of a global downturn on Africa's largest economy.

The bank also cut its 2012 growth forecast to 2.7 percent from 2.9 percent and said the risks to the outlook were negative.

"We had previously thought that we were at the bottom of an interest rate cycle but events unfolded in an unexpected way," Marcus said of the decision.

Economic analysts have speculated the cut could be the start of another cycle of monetary easing after the bank slashed rates by a cumulative 6.5 percentage points between 2008 and 2010 to spur growth after a recession.

"Further easing however cannot be taken for granted and will be contingent on changing global conditions and well as further inflation and growth developments," Marcus told an editors' forum, echoing comments she made at the Bank's annual general meeting on Friday.

"I should emphasize that it is also important for the markets to pick up the signals from the changing fundamentals in the economy. If the fundamentals or circumstances change all of a sudden, this may lead to a change in policy."

Source: http://news.yahoo.com/africa-rate-cuts-cant-taken-granted-marcus-083036263--sector.html

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Jordan opens camp to deal with more Syrian refugees

ZAATARI, Jordan (Reuters) - Jordan braced on Sunday for an expected new influx of refugees from the fighting in Syria by opening a camp with 2,000 tents to accommodate them near the border.

Diplomats say around 115,000 Syrians have fled their country, mostly to Turkey, Lebanon and Jordan, to escape the 17-month rebellion against President Bashar al-Assad.

The Jordanian authorities say around 130,000 Syrians have come to Jordan since the uprising began, but diplomats say not all of them are classified as refugees.

"We can only expect that more people will be coming across, more people who will be in need of assistance," Andrew Harper, representative for the United Nations Higher Commissioner for Refugees (UNHCR) in Jordan, said at the camp's opening.

"We are seeing women and children without their husbands, without their fathers, coming across the border," Harper said at the still-empty camp, the first to become operational for Syrian refugees, near the town of Mafraq, about 10 km (six miles) from the Syrian border.

Tens of thousands of Syrians have fled to Jordan through official border points or clandestinely crossed the mostly desert frontier.

Most have found accommodation on their own, or through Islamist charities and compatriots who had fled an earlier wave of repression by Assad's father, the late President Hafez al-Assad, in the 1980s.

Syrian troops have tried to prevent refugees from crossing by mining parts of the border, and in some cases, shooting at fleeing civilians, which has prompted Jordan to send armored reinforcements to the frontier.

Diplomats say there have been several instances of Jordanian and Syrian forces exchanging fire following the killing of refugees who had attempted to cross as they were in the "no-man's land" between the two countries.

(Reporting by Mohammad al-Ramahi; Editing by Michael Roddy)

Source: http://news.yahoo.com/jordan-opens-camp-deal-more-syrian-refugees-181128064.html

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Officials: Ebola breaks out in Uganda

KAMPALA, Uganda (AP) ? The deadly Ebola virus has killed 14 people in western Uganda this month, Ugandan health officials said on Saturday, ending weeks of speculation about the cause of a strange disease that had many people fleeing their homes.

The officials and a World Health Organization representative told a news conference in Kampala Saturday that there is "an outbreak of Ebola" in Uganda.

"Laboratory investigations done at the Uganda Virus Research Institute...have confirmed that the strange disease reported in Kibaale is indeed Ebola hemorrhagic fever," the Ugandan government and WHO said in joint statement.

Kibaale is a district in midwestern Uganda, where people in recent weeks have been troubled by a mysterious illness that seemed to have come from nowhere. Ugandan health officials had been stumped as well, and spent weeks conducting laboratory tests that were at first inconclusive.

On Friday, Joaquim Saweka, the WHO representative in Uganda, told The Associated Press that investigators were "not so sure" it was Ebola, and a Ugandan health official dismissed the possibility of Ebola as merely a rumor. It appears firm evidence of Ebola was clinched overnight.

Health officials told reporters in Kampala that the 14 dead were among 20 reported with the disease. Two of the infected have been isolated for examination by researchers and health officials. A clinical officer and, days later, her 4-month-old baby died from the disease caused by the Ebola virus, officials said.

Officials urged Ugandans to be calm, saying a national emergency taskforce had been set up to stop the disease from spreading far and wide.

There is no cure or vaccine for Ebola, and in Uganda, where in 2000 the disease killed 224 people and left hundreds more traumatized, it resurrects terrible memories. There have been isolated cases since, such as in 2007 when an outbreak of a new strain of Ebola killed at least 37 people in Bundibugyo, a remote district close to the Congolese border, but none as deadly as in 2000.

Ebola, which manifests itself as a hemorrhagic fever, is highly infectious and kills quickly. It was first reported in 1976 in Congo and is named for the river where it was recognized, according to the Centers for Disease Control and Prevention.

A CDC factsheet on Ebola says the disease is "characterized by fever, headache, joint and muscle aches, sore throat, and weakness, followed by diarrhea, vomiting, and stomach pain. A rash, red eyes, hiccups and internal and external bleeding may be seen in some patients."

Scientists don't know the natural reservoir of the virus, but they suspect the first victim in an Ebola outbreak gets infected through contact with an infected animal, such as a monkey.

The virus can be transmitted through direct contact with the blood or secretions of an infected person, or objects that have been contaminated with infected secretions. During communal funerals, for example, when the bereaved come into contact with an Ebola victim, the virus can be contracted, officials said, warning against unnecessary contact with suspected cases of Ebola.

In Kibaale, some villagers had started abandoning their homes in recent weeks to escape what they thought was an illness that had something to do with bad luck, because people were quickly falling ill and dying, and there was no immediate explanation, officials said.

Officials said now that they've verified Ebola in the area they can concentrate on controlling the disease. Ebola patients were being treated at the only major hospital in Kibaale, said Stephen Byaruhanga, the district's health secretary.

"Being a strange disease, we were shocked to learn that it was Ebola," Byaruhanga said. "Our only hope is that in the past when Ebola broke out in other parts of Uganda it was controlled."

The challenge, he said, was retaining the services of all the nurses and doctors who are being asked to risk their lives in order to look after the sick.

"Their lives are at stake," he said.

Officials also worry that other villagers suffering from other diseases might be afraid to visit the hospital for fear of catching Ebola, he said.

Source: http://news.yahoo.com/officials-ebola-breaks-uganda-123309607.html

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Raw Five-Point preview: July 30, 2012

All WWE programming, talent names, images, likenesses, slogans, wrestling moves, trademarks, logos and copyrights are the exclusive property of WWE, Inc. and its subsidiaries. All other trademarks, logos and copyrights are the property of their respective owners. ? 2012 WWE, Inc. All Rights Reserved. This website is based in the United States. By submitting personal information to this website you consent to your information being maintained in the U.S., subject to applicable U.S. laws. U.S. law may be different than the law of your home country. WrestleMania XXIX (NY/NJ) logo TM & ? 2012 WWE. All Rights Reserved. The Empire State Building design is a registered trademark and used with permission by ESBC.

Source: http://www.wwe.com/shows/raw/2012-07-30/five-point-preview

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thecrimereport: Ohio's 300 'Mayor's Courts': Backwoods Cash Machines or Legit Justice? http://t.co/dVkg5dwv

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Source: http://twitter.com/thecrimereport/statuses/229660104859987968

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Sunday, July 29, 2012

Tajik rebels surrender after threat of new assault

DUSHANBE (Reuters) - Rebels facing off against government troops in Tajikistan's volatile east began laying down their weapons on Sunday after the authorities threatened to launch a new offensive to capture a former warlord accused of killing a local security chief.

President Inomali Rakhmon had called a ceasefire late last Tuesday after heavy fighting, promising to pardon anyone who disarmed while demanding that the rebels handed over Tolib Ayombekov, the former warlord, along with three fighters.

A senior Tajik security official told Reuters on condition of anonymity on Sunday that the rebels had started to surrender at about 0200 GMT, handing over "dozens of guns".

"We now hope that everything will end peacefully," he said.

Tajikistan's interior ministry confirmed the news in a statement, saying: "Members of illegal armed units in the Gorno-Badakhshan region have started turning in their arms ... Those laying down their weapons are immediately amnestied."

Rakhmon had sent troops into the area on Tuesday in pursuit of former opposition field commander Ayombekov, accusing him of killing Major-General Abdullo Nazarov, the head of the Gorno-Badakhshan branch of the GKNB, successor of the Soviet-era KGB, on July 21.

Officials said the heavy fighting that followed killed 17 troops, 30 rebels and one civilian, in violence that raised concerns about the stability of the majority Muslim nation.

On Saturday - after several days of talks - the authorities issued a final warning, telling the rebels they would launch a new large-scale military offensive against them unless they surrendered.

"MAIN THING IS THAT THIS NOW ENDS PEACEFULLY"

However, not all of the authorities' demands were met.

"At this stage, there is no talk about the surrender of Ayombekov and other rebels accused of killing Nazarov," the same security source told Reuters on Sunday. "Militants say they are in Afghanistan, and we also do not exclude this."

"The main thing is that this (stand-off) now ends peacefully, and we will return to Ayombekov's capture later."

After Nazarov was killed, the government sent helicopters, armored vehicles and thousands of troops into the area. Nazarov's agency had accused Ayombekov's gang of smuggling drugs, tobacco and precious stones.

Ayombekov, who fought against Rakhmon in a 1992-97 civil war before receiving a government job in the peace deal that ended the conflict, denied any involvement in Nazarov's killing.

Fearing possible infiltration of Taliban-linked fighters who support Ayombekov, Tajikistan closed all its border crossings with Afghanistan, only allowing trucks carrying cargo for NATO troops there to pass.

Some analysts said that the assault - the first military operation on such a scale in almost two years - was a show of force by Rakhmon, whose control over parts of the Central Asian state remains tenuous 15 years after the end of the civil war.

Separated from Afghanistan by the Pyandzh river, Gorno-Badakhshan is an autonomous region where the authority of the central government is particularly fragile. Most of its 250,000 inhabitants sided with the opposition during the civil war.

Tajikistan is the poorest of 15 former Soviet republics. Tens of thousands died in its civil war, in which Rakhmon's Moscow-backed troops fought a loosely aligned opposition that included many Islamist fighters.

Former imperial master Russia still has 6,000 troops stationed in Tajikistan, its largest military deployment abroad and one which is meant to act as a bulwark against the threat of Islamist violence spilling across the Afghan border when NATO pulls its troops out in 2014.

(Writing by Dmitry Solovyov; Editing by Andrew Osborn)

Source: http://news.yahoo.com/tajik-rebels-surrender-threat-assault-071844560.html

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US Olympic womens soccer goalie Hope Solo wont face any discipline from team coach Pia Sundhage after Solo took to Twitter t...

SbB LIVE FROM LA (Jul 29, 2012 @ 7:21pm ET)

Comments | SbB Live RSS Feed
Sunday, July 29, 2012

7:15 PM: Scott Wolf of the L.A. Daily News notes that French swimmer Clement Lefert's gold medal in the 400m Sunday relay means that a USC athlete has won gold in every Olympics since 1912.

7:00 PM: A Lauderdale County (Alabama) judge dismissed a lawsuit filed by a former Hatton High School football coach after he was fired at the end of last season.

6:45 PM: U.S. Olympic women's soccer goalie Hope Solo won't face any discipline from team coach Pia Sundhage after Solo took to Twitter to complain about commenting from Brandi Chastain.

6:30 PM: In response to criticism against NBC for tape-delaying the Olympic opening ceremony & other events, someone has created an "NBC Delayed" Twitter account. First post on Sunday: "BREAKING: American colonists announce independence, King to respond."

6:15 PM: Singer Tom Jones had to cancel his Olympic celebration concert scheduled for Saturday in Hyde Park after contracting bronchitis.

6:00 PM: The Houston Astros defeated the Pittsburgh Pirates 9-5 Sunday to end their club-record 12-game losing streak.

5:45 PM: The Spanish men's soccer team was eliminated from the Olympics after Sunday's 1-0 defeat to Honduras, while Senegal gave Uruguay its first-ever Olympic defeat in a 2-0 win.

5:30 PM: The Cincinnati Reds say that play-by-play announcer Marty Brennaman will have his head shaved if the Reds beat the Rockies today. Brennaman made the pledge at the start of the season that he would do it if the Reds won 10 straight games.

5:15 PM: Dallas Cowboys owner Jerry Jones said Sunday he wants his team to return to its "glory hole" days.

5:00 PM: NASCAR driver Jimmie Johnson won his fourth Brickyard 400 title at the Indianapolis Motor Speedway on Sunday, tying the record set by Jeff Gordon.

4:45 PM: ESPN college basketball analyst Dick Vitale tweets that Illinois is "totally classless" for trying to recruit football players from Penn State.

4:30 PM: Iowa Hawkeyes RB De'Andre Johnson has been suspended indefinitely following his two arrests in the past three days. Johnson was cited Thursday for loud music at his home, and was arrested Saturday for speeding & evading police.

4:15 PM: U.S. Olympic swimmer Dana Vollmer set a new world record in the 100m butterfly Sunday. Vollmer's time of 55.98 was 0.08 seconds faster than the previous mark.

4:00 PM: "Breaking Bad" actor Bryan Cranston tweets some advice to Olympic swimmer Michael Phelps: "Channel your inner Walter White. As you look at the water imagine blue crystal and say to yourself, I AM the danger!."

3:45 PM: New York Jets LB Bart Scott says of Tim Tebow removing his top at practice: "I've never seen anybody decide to take their shirt off in the rain. Maybe it was holy water ... I don't know."

? previous entries

Source: http://www.sportsbybrooks.com/sbblive?eid=40239

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IPO Watch: Is Machester United a Good Investment? | Stocks on ...

Every fan dreams of owning a piece of there favorite professional sports team? Would you overpay for the privilege to say you own a piece of the New York Yankees? Dallas Cowboys? L.A. Lakers? Most fans would hop on that opportunity right away. Well for the rest of the world, soccer team Manchester United is their New York Yankees. Winner of 19 English Premier League Titles, Manchester United is the most glorified sports franchise of all-time, boasting well over 600 million supporters worldwide. And in less than a month, just about any of those 600 million supporters will be able to make one call or a simple click of the mouse and own shares of the iconic franchise. Buying shares of Man United will be a great idea to many for the obvious personal reasons but the real question is whether or not buying shares of Manchester United is a good investment at all?

Why is Manchester United Going to Be Listed on the New York Stock Exchange?

So let?s analyze why a famous British Soccer team is going to list and trade at the New York Stock Exchange. It starts with a rich owner, Malcolm Glazer, who has huge ambitions and aspirations for the club. Malcolm Glazer bought the team in 2005 for $1.2 billion and wants to go public, raise funds, and mitigate risks while still retaining control of the team. Something every investor would love to have the opportunity to do. Listing on the NYSE will give the Glazer family a dual-class share structure; allowing them to keep voting rights.? This model is very much similar to the structure the Murdoch family setup to keep control of News Corp (NASDAQ: NWSA). Listing on the London Stock Exchange would not allow this kind of setup which is why they have chosen to bring the British Soccer across the pond.

What Can We Expect as an Investment?

What?s not to like, Manchester United is a franchise that turns a profit every year and has a track record of being a solid equity investment. Man United has appreciated more than ?20%?annually for the 14 years it was traded prior to the Glazer family taking control and taking it private seven years ago.

Cash is king & Manchester United has serious debt woes. The lopsided stock-ownership structure is nothing to be worried of when you compare it to the franchise?s debt woes. Yes that?s right, Man United currently has $650 million in debt, a staggering number when you factor in that the club carried no debt every year before 2005 when the Glazer family gained ownership. Since then, the Glazer has leveraged the club quite a bit using these tactics to get the team, and since the acquisition have used it as a piggy bank of sorts.?

If the IPO is successful and raises the expected $300 million or more where will that money go? Being valued at $3 billion, the assumption is that most of that money will pay down the debt but some fans or future shareholders might have other plans. Fans hope the money raised goes towards some more exciting business moves such as acquiring top notch players to keep up with the rest of the league, lowering ticket prices, or improving the stadium grounds. Acquiring top talent is even more intense now after they lost to cross-town rival Manchester City, a team that was long one of the worst in the league until it was purchased by a group from Abu Dhabi who invested billions in acquiring the top players across the world and successfully turned the team into an instant winner.

Manchester United fans have been pressuring the club more and more to acquire top players but the club?s debt worries have sucked out hundreds of millions that the team use to use to improve the talent on the pitch. A main reason Manchester United isn?t the football powerhouse that use to dominate the league year in year out.

For sale: world-famous company that?s highly leveraged with anti-takeover provisions and no dividend or stock buyback plans in sight.

A large issue surrounding the IPO is future accountability. As result of the Jobs Act, foreigncompanies can take advantage of many loopholes. For example, Manchester United will not have to report results every quarter or give forward-looking guidance. Pretty sweet deal for ownership, but a serious issue for most investors.

Who wants to own shares of a company saddled with debt where even the largest shareholders hold no control. Many will still buy for the same reason people bought shares in the Green Bay Packers, a stock that is such a novelty that shares have no dividend and cannot be sold for a profit. There will be a large group of wealthy fans who love the team and want the power to say they own part of Man United. But that doesn?t mean they?ll make any money off it. So to investors, especially institutional ones it could be a tough sell. One thing Man United does have going for them is the fact that they?re an exclusive rarity that compares to nothing. Just think you could own a piece of Manchester United, the most glorified football team. For most diehard fans that?ll be an easy sell.

What other Sports Teams are Publicly Traded? While there are technically no other professional sports teams publicly traded in the U.S., investors can buy shares of Madison Square Garden (NASDAQ: MSG), which gives you ownership of the NBA?s New York Knicks, the NHL Rangers, a WNBA team, an arena and a TV network. Sorry, no Jeremy Lin though. Another similar company is Liberty Media (NASDAQ: LMCA) owns the Atlanta Braces baseball team, which is only one component of their huge portfolio of companies. Nintendo (NTDOY) owns most of the Seattle Mariners, Rogers Communications (RCI) a small piece of the Toronto Blue Jays. So technically all of these are indirect ways to owning a sports team. Outside the U.S., there are a handful of soccer teams that actively trade on other foreign global markets. For example, AJAX trades in the Netherlands; Juventus in Italy; Benfica in Portugal, and Fenerbache a lesser-known name listed in Turkey, but has an annualized return of almost 14 percent. Meanwhile the other mentioned teams all had negative annualized returns and have all been losing investments. The big question looming is where Manchester United will stand.

When will it be on the market? The worldwide roadshow is just beginning and Manchester United has elaborate plans to host a worldwide road show that will start in Europe and end in the U.S.? Pricing and trading is expected to begin at some point in August but due to recent reports of the IPO being a tough sale Manchester United has put the IPO on hold. While it?s technically on hold, things could change very soon as analysts expect the roadshow will start next week, speeding up the process in hopes to feed off of the U.S. markets big recent rally. That?s right around the time that Manchester United kicks off its regular season. Only time will tell on which will be the bigger winner, the team on the field or the team on the stock exchange.?

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Source: http://stocksonwallstreet.net/2012/07/ipo-watch-is-machester-united-a-good-investment/

billy crystal oscars 2012 angelina jolie oscars

Bath salts: Police raids net huge haul of synthetic drugs

Federal agents and state and local police made more than 90 arrests in nationwide raids. Experts say bath salts and other potent synthetic drugs are becoming popular, particularly among teens.?

By Stacy Teicher Khadaroo,?Staff Writer / July 27, 2012

Joseph M. Arabit, center, Special Agent in Charge of the DEA office in El Paso, speaks at a news conference announcing the results of Operation Log Jam Thursday, July 26, 2012 in El Paso, Texas. The series of raids Wednesday were part of a nationwide crackdown against manufacturers, distributors and vendors of synthetic designer drugs.

Rudy Gutierrez/AP Photo/The El Paso Times

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Federal drug agents and state and local police staged raids across the US, yielding more than 90 arrests and what they said were major seizures of potent, synthetic drugs including so-called ?bath salts.?

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New York, Illinois, and Texas had the highest number of cities with "take-down sites,? as part of what the federal Drug Enforcement Agency called Operation Log Jam. The DEA said 5 million packets of the drugs were seized from both drug retailers and manufacturing operations, as well as chemicals that could have produced about 14 million more such packets.

?This enforcement action has disrupted the entire illegal industry, from manufacturers to retailers,? DEA Administrator Michele Leonhart said in a statement Thursday.

The crackdown targeted two categories of drugs. One, known as synthetic cannabinoids, includes smokeable substances commonly called ?K2? and ?Spice.? They are typically made up of plant material coated with dangerous psychoactive compounds. Among 12th -graders these are the second most commonly used illicit drug, with 11.4 percent using it, according to a 2011 survey cited by the Office of National Drug Control Policy.?

The other category was synthetic cathinones often known as ?bath salts? which are sold with street names like ?Vanilla Sky? or ?Purple Wave.? They can produce hallucinations, suicidal thoughts, violent behavior, and physical ailments, drug-abuse prevention experts say, and users have also reported extreme paranoia, ?and reduced motor control.

The drugs are popular, especially with teens, because they?ve been promoted heavily online as legal and not harmful, says Mike Townsend, executive vice president of The Partnership for A Drug-Free America. ?But it is very dangerous.?

The crackdown is encouraging and could slow the supply of such drugs, says Mr. Townsend. But ?it?s not a long-term solution?. Supply reduction can?t work by itself. You have to reduce demand too. We have to educate kids and parents.?

According to the American Association of Poison Control Centers, the number of calls related to bath salt drugs received by poison control centers across the country spiked from 304 in 2010 to 6,138 in 2011, and then started tapering off in 2012. Nearly 7,000 calls also came in about the synthetic drugs in 2011.

The synthetic drugs can have dramatic effects within just 15 minutes of being ingested or snorted. Townsend?s organization has received calls from frightened mothers who say they have to ?sit on the child?s chest while he?s thrashing about.?

The makers of the drugs took advantage of compounds that were originally developed for medical research, but have never been tested or approved for human consumption, says David Shurtleff, acting deputy director of the National Institute on Drug Abuse.

?Spice? is more potent than marijuana, Dr. Shurtleff says, and all the synthetic drugs have shown up linked to more emergency room visits. There could be long-term toxic effects as well, he says. ?You?re really gambling with the health of your brain and your body by taking these drugs.?

A law signed this month by President Obama bans more than two dozens substances used in these drugs as Schedule 1 controlled substances, similar to heroin, enabling enhanced prosecution. The DEA is also authorized to treat substances as controlled if they are proven to be chemically similar to banned drugs. Many states have also changed their laws to try to account for the new trend.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/Zif-jkRaQLo/Bath-salts-Police-raids-net-huge-haul-of-synthetic-drugs

kennedy demi moore